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Human Male Sex: Endocrine Disruption and Male Reproductive Wellness

Human Male Sex: Endocrine Disruption and Male Reproductive Wellness

Human Male Sex: Endocrine Disruption and Male Reproductive Wellness

9.1 Introduction

Male sexuality is decided genetically during the time of fertilization because of the existence of a Y chromosome into the spermatozoan since it fuses utilizing the X-chromosome-containing ovum, as well as the sex-determining area associated with Y chromosome (SRY) then drives the bipotential gonad associated with embryo in order to become a testis through hormone-independent mechanisms 1,2. But, after the testis that is early created, growth of the total male phenotype, including further testicular development (masculinization), becomes entirely influenced by a complex community of hormonal signals, specially hormones secreted through the testes 2. People who lack any gonads are phenotypically female 1 and endocrine intervention is necessary to alter the standard feminine phenotype to be male 2. This will make both development and upkeep of masculinization in danger of endocrine-disrupting impacts after all developmental phases from very very very early embryo to adulthood; in particular, interruption of very early embryonic developmental processes might have consequences for male health that is reproductive adult life 2. This chapter will deal with the results of endocrine interruption for growth of the tract that is urogenital for sperm production. It’ll talk about the cap cap ability of endocrine-disrupting chemicals (EDCs) to carry breast that is about inappropriate (gynecomastia), alterations to puberty, and hyperplasia in prostatic muscle ( Figure 9.1 ). Daha fazla hakkındaHuman Male Sex: Endocrine Disruption and Male Reproductive Wellness oku